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New Trial Explores Peptide-Based Combination to Reawaken Immunotherapy in Resistant Cancers
A new Phase I/II trial will test whether combining bexmarilimab with nivolumab can help restore immune system effectiveness in melanoma and non-small cell lung cancer patients whose disease has stopped responding to standard immunotherapy.
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New Clinical Trial Launches to Study Efruxifermin for Advanced Liver Scarring from NASH/MASH
A new multi-center clinical trial is underway to evaluate efruxifermin, an investigational peptide-based therapy, in patients with compensated cirrhosis caused by NASH/MASH.
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New Phase 2/3 Trial Launches to Explore BNT327 Combination Therapy for Lung Cancer
A newly registered Phase 2/3 study will investigate whether BNT327, combined with chemotherapy and other investigational agents, can improve outcomes for patients with first-line non-small cell lung cancer.
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Rollover Trial Ensures Continued Access to Promising KRAS-Targeted Peptide Therapy Opnurasib
A new Novartis-sponsored rollover study will allow patients who are already benefiting from opnurasib (JDQ443) to continue their treatment while safety monitoring continues.
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New Clinical Trial Explores Peptide-Targeted Radiotherapy for GRPR-Positive Tumors
A new Phase 1-1b study will investigate a peptide-receptor targeted radioligand approach for treating advanced solid tumors that express the GRPR receptor, combining precision imaging with targeted therapy.
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New Clinical Trial Explores Long-Term Tirzepatide Treatment for Adolescents with Obesity
A new study, SURMOUNT-ADOLESCENTS-2, will examine how extended tirzepatide treatment combined with healthy lifestyle habits affects bodyweight and cardiovascular risk factors in teens with obesity.
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New Clinical Trial Explores Combination Therapy for Metastatic Soft Tissue Sarcoma
A new clinical trial is investigating whether combining zanzalintinib with immunotherapies ipilimumab and nivolumab could offer a promising treatment strategy for patients with metastatic soft tissue sarcoma.
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New Study to Explore Real-World Impact of Inbrija® on Parkinson’s OFF Episodes
A new multi-country study will examine how people with Parkinson’s disease experience OFF episodes and how treatment with Inbrija® affects their daily lives and quality of life. The research aims to better capture the real-world patient perspective on this inhaled therapy.
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Exploring Clinical Trials: A Pathway to Accessing Investigational Peptide Retatrutide
Retatrutide, a promising investigational peptide being studied for weight management, may be accessible to eligible participants through ongoing clinical trials. Here’s what interested individuals should know about this research pathway.
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Mazdutide Shows Promising Results for Weight and Waist Reduction in Major Trial
A large clinical trial found that the peptide-based obesity drug mazdutide significantly reduced both body weight and waist circumference in participants, offering new hope for metabolic health management.