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New Clinical Trial Explores Base-Edited Stem Cell Therapy as Potential Cure for WHIM Syndrome
Researchers are launching a trial that uses base-editing technology to correct the CXCR4 gene mutation responsible for WHIM syndrome, offering hope for a one-time curative treatment for this rare immune disorder.
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New Clinical Trial Explores BMS-986504 Combined with Standard Cancer Therapy for Solid Tumors
A newly launched study is investigating whether BMS-986504, used alongside standard-of-care treatments, can safely help patients with advanced MTAP-deleted solid tumors.
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New Trial Explores Blood Test to Personalize Immunotherapy After Urothelial Cancer Surgery
A phase II/III trial is testing whether circulating tumor DNA (ctDNA) in the blood can help doctors identify which urothelial cancer patients benefit most from immunotherapy after surgery. The approach could lead to more precise, personalized cancer care.
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New Clinical Trial Explores Intranasal Insulin as a Potential Support for Spinal Cord Injury Recovery
A new study is investigating whether a nasal spray form of insulin, already used safely in other patient groups, could be a safe and feasible option for people living with spinal cord injury.
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New Clinical Trial Explores Combination Therapy for Advanced Colorectal Cancer
A new clinical trial is investigating whether combining liposomal irinotecan with TAS102 and bevacizumab can help patients with treatment-resistant metastatic colorectal cancer. The study offers a potential new option for patients who have exhausted standard therapies.
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New Clinical Trial Explores Combination Therapy for Virus-Related Cancers
A new NIH-sponsored trial is testing whether pairing pomalidomide with the immunotherapy nivolumab can safely and effectively treat a range of cancers caused by viruses, including in patients with HIV.
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New Clinical Trial Explores Peptide-Based Therapy for Metastatic Colorectal Cancer
A new global trial is investigating whether adding the investigational antibody-drug conjugate telisotuzumab adizutecan to standard chemotherapy regimens can improve outcomes for patients with metastatic colorectal cancer.
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New Research Explores How Peptides Could Help Ease Chronic Pain in People Living with HIV
A new clinical trial is investigating whether changes in the body’s natural opioid peptides contribute to chronic pain in people with HIV, opening the door to potential new peptide-based therapies.
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New Clinical Trial Brings Promising Lymphoma Therapy Epcoritamab to Patients in China
A new study is evaluating subcutaneous epcoritamab—alone and combined with standard chemotherapy regimens—for adults with B-cell Non-Hodgkin Lymphoma across 21 sites in China, expanding access to this investigational immunotherapy.
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New Phase 3 Trial Launches to Study Growth Hormone Therapy for Children with Idiopathic Short Stature
A multicenter Phase III trial is now evaluating Sinotropin AQ, a human growth hormone injection, as a potential treatment to improve height velocity in children with idiopathic short stature.